Pediatric Liver Transplant

Pediatric Liver Transplant


Pediatric Liver Transplant: Evaluation, Surgery, and Recovery

A pediatric liver transplant is a surgery performed on infants and kids at a young age. It is a more sensitive and complex procedure for treating babies' livers. Also, it is a surgical process where the affected part of the child's liver is replaced with a portion of adult or kid live donor to restore the normal liver in the baby. For a child liver transplant, a donor must qualify the national donor criteria to donate a liver or portion of their liver for a child's liver transplantation.

A family member or a parent can also donate a liver for the child's liver transplantation process. Donating part of your liver to a family member requires meeting the live liver donor criteria including the liver donor age limit. There can be several reasons why a child may need liver transplantation. There can be several causes why a child may need liver transplantation. The most common cause of pediatric liver transplant is biliary atresia, a rare liver disease in infants and babies. However, proper care and timely diagnosis can ensure a safe and successful transplant. Today, we will discuss everything about a child's liver transplant, including conditions indicating a liver transplant, common symptoms, procedure, donor qualifications, and more.

Parents' Review After Their Baby's Liver Transplant Surgery in India

Mr. Rachid Echadli and Mrs. Fatima Zahra came all the way from Morocco to India for their daughter's liver transplant surgery. Their baby was only four months old when she was diagnosed with congenital liver disease. The only option was a liver transplant to cure the liver cirrhosis the baby had. Dr. Giriraj Bora has done the surgery successfully at JCI-accredited Artemis Hospital in Delhi, India. The mother was the living liver donor. Both the mother and the baby are well now. Listen to their words by clicking the video.

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Overview of Pediatric Liver Transplant

A pediatric liver transplant is a complex and delicate surgical procedure that replaces a diseased liver (portion of the liver) of a child or infant with a healthy liver or part of the liver from a donor. A child liver transplant can be done with a deceased donor transplant or a live donor transplant.

In a deceased donor transplant, the liver or portion of the liver is taken from a donor who has recently died. On the other hand, in a live donor transplant, the liver or part of the liver is sourced from a living person who has volunteered for the liver donation. Also, the potential donors must qualify for the donor criteria. Before surgery, they must be physically healthy and undergo all the essential tests, such as blood, sugar, and other tests.

Conditions for Pediatric Liver Transplantation

Children and infants need to undergo a liver transplant due to several reasons or conditions. They might have or have been suffering from a disease that has damaged the liver or caused impairment. Also, some rare disease that does not harm life but can affect other organs requires a liver transplant. In addition, a large tumor in the liver that cannot be removed without removing the liver needs a liver transplant.

Biliary atresia is the most common cause of pediatric liver transplant. The other common reasons are as follows:

  • Hepatoblastoma
  • Alagille syndrome
  • Primary sclerosing cholangitis
  • Alpha-1 antitrypsin deficiency
  • Acute liver failure

Symptoms of Liver Diseases in Children

Pediatric liver transplant mostly requires cases where the liver of the baby is damaged, whether wholly or partially, due to disease, genetics, birth complications, and so on. A damaged or affected liver can cause several symptoms that indicate that your child may need an infant liver transplant.

Here are some common symptoms that suggest your kid may need an infant liver transplant-

  • Gastrointestinal problems
  • Feverish
  • Fatigue
  • Loss of appetite
  • Nausea and vomiting
  • Pain in abdomen
  • Jaundice
  • Dark urine
  • Bruising and bleeding easily
  • Itching all over the body
  • Swollen abdomen as the fluid begins to build up
  • Brain problems, confusion, Irritability, and encephalopathy.

Liver transplant evaluation procedure for a child

The pediatric liver transplant evaluation process can be overwhelming for a child's parent. The procedure is time-consuming and requires a wide range of tests before the transplantation occurs. Here are some standard details of pediatric liver transplants happens -

  • Vaccination review or immunization
  • Blood test
  • Chest x-ray to monitor lung and heart function
  • Electrocardiogram
  • Vital signs study
  • CAT liver scan
  • Viral studies such as hepatitis A, hepatitis B, HSV HIV, and chicken pox.
  • Liver ultrasound

In addition to all the technical tests, parents of an infant liver transplant patient may need pre-surgical psychological counseling for evolution.

Pediatric Live-Donor Liver Transplant: Definition

With the advancement of medical science, many new and effective techniques have surfaced for human welfare, and one among them is a pediatric live-donor liver transplant. A live liver donor transplant is a surgical procedure where a liver or portion of the liver (of a child or infant) is removed, which is no longer functioning, and replaced with a new and healthy liver or part of the liver from a live donor.

Earlier liver transplants were used to replace the affected liver with a healthy liver from a diseased donor. But now, any qualified person can donate a liver for a pediatric liver transplant. Also, these types of liver transplants have a higher success rate than the previous one (pediatric diseased donor liver transplant). The donor surgery can be both open as well as minimally invasive procedures. CureIndia surgeons evaluate the donor and do the suitable procedure.?

Living pediatric liver donor qualifications

Getting a liver from a live donor for your child's liver transplant has a higher success rate. However, only some are eligible for the task. A donor must meet all the essential living liver donor qualifications to donate a liver for a pediatric liver transplant. Here are the crucial criteria for a live liver donor willing to donate liver for a liver transplant. Check all these criteria if you are considering donating part of your liver to a family member.

  • The average live liver donor age limit is between 18 to 60.
  • Donors must be free from alcohol for at least six months.
  • The donor must not have any liver disease or active infection.
  • They must have a healthy body weight.
  • Donors must have a healthy mental and physical state.
  • They must have a compatible blood type.
  • Have healthy kidney and liver function.
  • Have sufficient social support.
  • Have proper health insurance support.
  • Willing to be committed for the entire procedure, from pre-surgery evolution to surgery and recovery.

Advantages of live pediatric liver-donor

A portion of the liver from a deceased or alive person can be used for an infant liver transplant. However, there are many benefits of pediatric live-donor liver transplant. Here are some benefits of getting a live liver donor.

  • Scheduling a date for liver surgery for an infant becomes more accessible with a clear discussion between the liver donor, the recipient, and the transplantation team.
  • For end-stage liver diseases, live donor surgery can be life-saving.
  • It also helps people on the liver transplant waiting list quickly get livers.
  • Living liver donors also feel suitable for positively impacting the lives of others.
  • Getting a live liver donation for an infant's liver surgery reduces the recovery time. A live liver also starts functioning quickly after the surgery.

Best Pediatric Liver Transplant Surgeons in India

When deciding on a liver transplant for children in India, knowing the surgeon is extremely important. Only an expert surgeon whom you can trust should be chosen for your child's treatment. CureIndia liver transplant surgeons are some of the few specialists.

1. Dr. Giriraj Bora

Dr. Giriraj Bora has an experience of over 1500 liver transplantations. He has expertise in gastrointestinal diseases, living donor liver surgery, pediatric liver surgery, etc.

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Successful Pediatric Liver Transplants by Dr Giriraj Bora

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2. Dr. Vivek Vij

Dr. Vivek Vij is a pioneer in liver transplant surgery in India. With his practices, Dr. Vivek Vij has achieved a 100% donor safety profile. He has performed more than 2500 liver transplants.?

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3. Dr. Abhideep Chaudhary

Dr. Abhideep Chaudhary is a renowned liver transplant surgeon in India. He aspires to bring positive changes in his patients? lives. He has expertise in pediatric liver surgery.

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4. Dr. Arvinder Singh Soin

Dr. Arvinder Singh Soin is the leading and most experienced liver transplant surgeon in India. He performs almost 25-30 liver transplant surgeries per month with a high success rate.

Dr AS Soin - Best Liver Specialist in India  

5. Dr. Subhash Gupta

Dr. Subhash Gupta is well-known for liver transplant surgery around the globe. In 2013, with his team, he successfully conducted 300 living donor liver transplants in New Delhi.

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Preparation for the surgery

Physical and mental health evaluation of both the donor and the recipient is necessary before considering the transplant. Different transplant teams will be assigned to care for the recipient and the donor. The procedure of living liver transplant surgery for an infant can be life-saving, but it also has some risks. Certain aspects like the compatibility of blood groups, physical and mental health, organ size, and age (both donor and recipient) should be considered before the transplant.

The procedure of pediatric live-donor liver transplant surgery

The surgery will begin only after your child has responded to the anesthesia and IV lines have been inserted. A registered nurse will monitor your child's vital signs and urine output throughout the procedure. A pediatric surgeon, anaesthesiologist, and other technicians will be in the operating room.

The pediatric surgeon will start the procedure by applying antiseptic and putting drapes on the surface of the operating site. After that, the surgeon will remove the non-functional liver and transplant the new, healthy liver in its place. The new liver should look soft and pink as blood will flow into it after the vessels are connected. The next step will be joining the bile ducts of the recipient and the donor's liver. Blood products will be provided to your child throughout the process if needed.

The procedure generally lasts for 4-8 hours. A transplant team member will update you about the surgery once every hour. After completing the course, your child will be sent to the Paediatric Intensive Care Unit.

Recovery and rehabilitation after liver transplant surgery

Both the recipient and the donor go through surgical procedures for pediatric liver transplant. Here, we will discuss the recovery periods for liver transplant donors and recipients.

An older child should stay for at least ten days, and an infant for 10-14 weeks in the hospital after the pediatric liver transplant. During this time, they receive care from the Paediatric Intensive Care Unit and are monitored by physicians and nurses.

A donor of a liver transplant also needs to stay in the hospital for 5-7 days and pause their work for 4-6 weeks for recovery from donating liver. They can resume their everyday lives after six weeks of the surgery.

To prepare for the procedure, the infant or child recipient will be given IV fluids through an IV line to draw back the blood. You may also need to sign consent forms for the surgery and anesthesia.

Pediatric Liver Transplant FAQs

Is a liver transplant safe for babies?

Yes, a liver transplant is safe for babies. But your doctor may suggest delaying the procedure. They might prefer that the baby grow up a bit.

How long do pediatric liver transplant patients live?

Surviving after a pediatric liver transplant is a lifelong process. The transplanted piece of liver grows. It grows as a child (the recipient) grows up. But rejection episodes are pretty standard.

Can a child receive a liver from an adult?

Yes, a child can receive a piece of liver from a living or deceased adult. However, the donor should not be obese. The blood groups of the donor and the recipient should match.

How successful are liver transplants in kids?

Recent research shows that the success rate of infant liver transplants is relatively high. Usually, 95% of paediatric liver transplant patients survive for five years.

How long is a hospital stay after a paediatric liver transplant?

Your child's stay in the hospital after a liver transplant can vary. It depends on their age. An infant's hospital stay after a liver transplant should be 10-14 weeks. Older children may need ten days of care in the hospital.

What disqualifies you from donating your liver?

A person with liver disease. A person with ailments like diabetes, cancer near the liver, or heart disease. All of these can disqualify a person to be a liver transplant donor.